FOXN4 Back

forkhead box N4

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NCBI Description of FOXN4

Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008].

Community Annotation of FOXN4 Add / Edit FOXN4: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


FOXN4 is highly significantly mutated in
FOXN4 is significantly mutated in
FOXN4 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for FOXN4