FOXL2 Back

forkhead box L2

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NCBI Description of FOXL2

This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of FOXL2 Add / Edit FOXL2: Annotations

No community annotations yet for FOXL2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FOXL2 is highly significantly mutated in
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FOXL2 is significantly mutated in
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FOXL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FOXL2