FOXA3 Back

forkhead box A3

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NCBI Description of FOXA3

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.

Community Annotation of FOXA3 Add / Edit FOXA3: Annotations

No community annotations yet for FOXA3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FOXA3 is highly significantly mutated in
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FOXA3 is significantly mutated in
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FOXA3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FOXA3