FN3K Back

fructosamine 3 kinase

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NCBI Description of FN3K
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FN3K is highly significantly mutated in
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FN3K is significantly mutated in
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FN3K is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FN3K