FLT4 Back

fms-related tyrosine kinase 4

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NCBI Description of FLT4
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.

Community Annotation of FLT4 Add / Edit FLT4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FLT4 is highly significantly mutated in
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FLT4 is significantly mutated in
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FLT4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FLT4