FLT3LG Back

fms-related tyrosine kinase 3 ligand

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FLT3LG
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011].

Community Annotation of FLT3LG Add / Edit FLT3LG: Annotations

No community annotations yet for FLT3LG.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FLT3LG is highly significantly mutated in
(none)
FLT3LG is significantly mutated in
(none)
FLT3LG is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FLT3LG