FLII Back

flightless I homolog (Drosophila)

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NCBI Description of FLII

This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Community Annotation of FLII Add / Edit FLII: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FLII is highly significantly mutated in
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FLII is significantly mutated in
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FLII is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FLII