FLCN Back

folliculin

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FLCN
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Community Annotation of FLCN Add / Edit FLCN: Annotations

No community annotations yet for FLCN.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FLCN is highly significantly mutated in
(none)
FLCN is significantly mutated in
(none)
FLCN is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FLCN