FKBP6 Back

FK506 binding protein 6, 36kDa

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NCBI Description of FKBP6
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male meiosis.

Community Annotation of FKBP6 Add / Edit FKBP6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FKBP6 is highly significantly mutated in
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FKBP6 is significantly mutated in
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FKBP6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FKBP6