FKBP2 Back

FK506 binding protein 2, 13kDa

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NCBI Description of FKBP2

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of FKBP2 Add / Edit FKBP2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


FKBP2 is highly significantly mutated in
FKBP2 is significantly mutated in
FKBP2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for FKBP2