FKBP1B Back

FK506 binding protein 1B, 12.6 kDa

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FKBP1B

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.

Community Annotation of FKBP1B Add / Edit FKBP1B: Annotations

No community annotations yet for FKBP1B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FKBP1B is highly significantly mutated in
(none)
FKBP1B is significantly mutated in
(none)
FKBP1B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FKBP1B