FKBP11 Back

FK506 binding protein 11, 19 kDa

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NCBI Description of FKBP11
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008].

Community Annotation of FKBP11 Add / Edit FKBP11: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FKBP11 is highly significantly mutated in
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FKBP11 is significantly mutated in
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FKBP11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FKBP11