FIS1 Back

fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)

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NCBI Description of FIS1
The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission (James et al., 2003 [PubMed 12783892]).[supplied by OMIM, Mar 2008].

Community Annotation of FIS1 Add / Edit FIS1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FIS1 is highly significantly mutated in
(none)
FIS1 is significantly mutated in
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FIS1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FIS1