FIGLA Back

folliculogenesis specific basic helix-loop-helix

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NCBI Description of FIGLA
This gene encodes a protein that functions in postnatal oocyte-specific gene expression. The protein is a basic helix-loop-helix transcription factor that regulates multiple oocyte-specific genes, including genes involved in folliculogenesis and those that encode the zona pellucida. Mutations in this gene cause premature ovarian failure type 6.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FIGLA is highly significantly mutated in
(none)
FIGLA is significantly mutated in
(none)
FIGLA is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FIGLA