FIBP Back

fibroblast growth factor (acidic) intracellular binding protein

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NCBI Description of FIBP

Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of FIBP Add / Edit FIBP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FIBP is highly significantly mutated in
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FIBP is significantly mutated in
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FIBP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FIBP