FHOD1 Back

formin homology 2 domain containing 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FHOD1
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines.

Community Annotation of FHOD1 Add / Edit FHOD1: Annotations

No community annotations yet for FHOD1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FHOD1 is highly significantly mutated in
(none)
FHOD1 is significantly mutated in
(none)
FHOD1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FHOD1