FHL5 Back

four and a half LIM domains 5

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NCBI Description of FHL5
The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Alternative splicing results in multiple transcript variants encoding the same protein.

Community Annotation of FHL5 Add / Edit FHL5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FHL5 is highly significantly mutated in
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FHL5 is significantly mutated in
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FHL5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FHL5