FGL2 Back

fibrinogen-like 2

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NCBI Description of FGL2

The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.

Community Annotation of FGL2 Add / Edit FGL2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


FGL2 is highly significantly mutated in
FGL2 is significantly mutated in
FGL2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for FGL2