FGL1 Back

fibrinogen-like 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FGL1
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.

Community Annotation of FGL1 Add / Edit FGL1: Annotations

No community annotations yet for FGL1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FGL1 is highly significantly mutated in
(none)
FGL1 is significantly mutated in
(none)
FGL1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FGL1