FGF5 Back

fibroblast growth factor 5

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FGF5
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of FGF5 Add / Edit FGF5: Annotations

No community annotations yet for FGF5.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FGF5 is highly significantly mutated in
(none)
FGF5 is significantly mutated in
(none)
FGF5 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FGF5