FGF14 Back

fibroblast growth factor 14

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NCBI Description of FGF14

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of FGF14 Add / Edit FGF14: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FGF14 is highly significantly mutated in
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FGF14 is significantly mutated in
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FGF14 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FGF14