FGF1 Back

fibroblast growth factor 1 (acidic)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FGF1
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Community Annotation of FGF1 Add / Edit FGF1: Annotations

No community annotations yet for FGF1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FGF1 is highly significantly mutated in
(none)
FGF1 is significantly mutated in
(none)
FGF1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FGF1