NCBI Description of FERMT3
|Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.|
Community Annotation of FERMT3 Add / Edit FERMT3: Annotations
No community annotations yet for FERMT3.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.