FCRLA Back

Fc receptor-like A

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NCBI Description of FCRLA
This gene encodes a protein similar to receptors for the Fc fragment of gamma immunoglobulin (IgG). These receptors, referred to as FCGRs, mediate the destruction of IgG-coated antigens and of cells induced by antibodies. This encoded protein is selectively expressed in B cells, and may be involved in their development. This protein may also be involved in the development of lymphomas. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Community Annotation of FCRLA Add / Edit FCRLA: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCRLA is highly significantly mutated in
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FCRLA is significantly mutated in
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FCRLA is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCRLA