FCRL2 Back

Fc receptor-like 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FCRL2

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Community Annotation of FCRL2 Add / Edit FCRL2: Annotations

No community annotations yet for FCRL2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCRL2 is highly significantly mutated in
(none)
FCRL2 is significantly mutated in
(none)
FCRL2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FCRL2