FCRL1 Back

Fc receptor-like 1

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NCBI Description of FCRL1
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.

Community Annotation of FCRL1 Add / Edit FCRL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCRL1 is highly significantly mutated in
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FCRL1 is significantly mutated in
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FCRL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCRL1