FCN2 Back

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

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NCBI Description of FCN2

The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of FCN2 Add / Edit FCN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCN2 is highly significantly mutated in
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FCN2 is significantly mutated in
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FCN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FCN2