FCGR3B Back

Fc fragment of IgG, low affinity IIIb, receptor (CD16b)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FCGR3B
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

Community Annotation of FCGR3B Add / Edit FCGR3B: Annotations

No community annotations yet for FCGR3B.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCGR3B is highly significantly mutated in
(none)
FCGR3B is significantly mutated in
(none)
FCGR3B is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCGR3B