FCGR2C Back

Fc fragment of IgG, low affinity IIc, receptor for (CD32)

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NCBI Description of FCGR2C

This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCGR2C is highly significantly mutated in
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FCGR2C is significantly mutated in
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FCGR2C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FCGR2C