FCGR2B Back

Fc fragment of IgG, low affinity IIb, receptor (CD32)

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NCBI Description of FCGR2B
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of FCGR2B Add / Edit FCGR2B: Annotations

No community annotations yet for FCGR2B.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCGR2B is highly significantly mutated in
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FCGR2B is significantly mutated in
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FCGR2B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCGR2B