FCGR1B Back

Fc fragment of IgG, high affinity Ib, receptor (CD64)

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NCBI Description of FCGR1B
Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of FCGR1B Add / Edit FCGR1B: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCGR1B is highly significantly mutated in
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FCGR1B is significantly mutated in
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FCGR1B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCGR1B