FCER2 Back

Fc fragment of IgE, low affinity II, receptor for (CD23)

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NCBI Description of FCER2
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Community Annotation of FCER2 Add / Edit FCER2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCER2 is highly significantly mutated in
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FCER2 is significantly mutated in
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FCER2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCER2