FCER1A Back

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FCER1A
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.

Community Annotation of FCER1A Add / Edit FCER1A: Annotations

No community annotations yet for FCER1A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FCER1A is highly significantly mutated in
(none)
FCER1A is significantly mutated in
(none)
FCER1A is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FCER1A