NCBI Description of FBXO34
|Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].|
Community Annotation of FBXO34 Add / Edit FBXO34: Annotations
No community annotations yet for FBXO34.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.