FBP1 Back

fructose-1,6-bisphosphatase 1

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NCBI Description of FBP1

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.

Community Annotation of FBP1 Add / Edit FBP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


FBP1 is highly significantly mutated in
FBP1 is significantly mutated in
FBP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for FBP1