FBLN2 Back

fibulin 2

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NCBI Description of FBLN2

This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FBLN2 is highly significantly mutated in
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FBLN2 is significantly mutated in
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FBLN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FBLN2