FATE1 Back

fetal and adult testis expressed 1

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NCBI Description of FATE1

This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FATE1 is highly significantly mutated in
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FATE1 is significantly mutated in
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FATE1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FATE1