FASTKD3 Back

FAST kinase domains 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of FASTKD3
This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants.

Community Annotation of FASTKD3 Add / Edit FASTKD3: Annotations

No community annotations yet for FASTKD3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FASTKD3 is highly significantly mutated in
(none)
FASTKD3 is significantly mutated in
(none)
FASTKD3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FASTKD3