FARSB Back

phenylalanyl-tRNA synthetase, beta subunit

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NCBI Description of FARSB
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FARSB is highly significantly mutated in
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FARSB is significantly mutated in
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FARSB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FARSB