FAM38B Back

family with sequence similarity 38, member B

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NCBI Description of FAM38B
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 [PubMed 20813920]).[supplied by OMIM, Nov 2010]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. There are no full-length transcripts representing this gene; this RefSeq is predicted based on a combination of partial human and mouse transcript alignments, but it is unclear if this exon combination exists in vivo.

Community Annotation of FAM38B Add / Edit FAM38B: Annotations

No community annotations yet for FAM38B.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FAM38B is highly significantly mutated in
(none)
FAM38B is significantly mutated in
(none)
FAM38B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FAM38B