FAM19A3 Back

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

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NCBI Description of FAM19A3

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of FAM19A3 Add / Edit FAM19A3: Annotations

No community annotations yet for FAM19A3.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FAM19A3 is highly significantly mutated in
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FAM19A3 is significantly mutated in
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FAM19A3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for FAM19A3