FABP5 Back

fatty acid binding protein 5 (psoriasis-associated)

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NCBI Description of FABP5
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.

Community Annotation of FABP5 Add / Edit FABP5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

FABP5 is highly significantly mutated in
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FABP5 is significantly mutated in
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FABP5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for FABP5