F2R Back

coagulation factor II (thrombin) receptor

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NCBI Description of F2R

Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


F2R is highly significantly mutated in
F2R is significantly mutated in
F2R is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for F2R