EXT2 Back

exostoses (multiple) 2

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NCBI Description of EXT2

This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Community Annotation of EXT2 Add / Edit EXT2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


EXT2 is highly significantly mutated in
EXT2 is significantly mutated in
EXT2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for EXT2