exosome component 9

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NCBI Description of EXOSC9

This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants.

Community Annotation of EXOSC9 Add / Edit EXOSC9: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


EXOSC9 is highly significantly mutated in
EXOSC9 is significantly mutated in
EXOSC9 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for EXOSC9