EXOSC8 Back

exosome component 8

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NCBI Description of EXOSC8
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6.

Community Annotation of EXOSC8 Add / Edit EXOSC8: Annotations

No community annotations yet for EXOSC8.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EXOSC8 is highly significantly mutated in
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EXOSC8 is significantly mutated in
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EXOSC8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EXOSC8