endo/exonuclease (5'-3'), endonuclease G-like

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NCBI Description of EXOG

This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

Community Annotation of EXOG Add / Edit EXOG: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


EXOG is highly significantly mutated in
EXOG is significantly mutated in
EXOG is near significance in

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Data details

Mutation list for EXOG