EXO1 Back

exonuclease 1

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NCBI Description of EXO1
This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

Community Annotation of EXO1 Add / Edit EXO1: Annotations

No community annotations yet for EXO1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

EXO1 is highly significantly mutated in
(none)
EXO1 is significantly mutated in
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EXO1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for EXO1