ESM1 Back

endothelial cell-specific molecule 1

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NCBI Description of ESM1
This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of ESM1 Add / Edit ESM1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ESM1 is highly significantly mutated in
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ESM1 is significantly mutated in
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ESM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ESM1