ERF Back

Ets2 repressor factor

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NCBI Description of ERF

Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 [PubMed 9192842]). For further information on ETS transcription factors, see ETS1 (MIM 164720).[supplied by OMIM, Mar 2008].

Community Annotation of ERF Add / Edit ERF: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ERF is highly significantly mutated in
(none)
ERF is significantly mutated in
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ERF is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ERF